We've actually considered that, but space is at a premium in our house and yard. My yard is literally about the size of a largish "galley"-shaped kitchen, and our property is wedged at the end of a right-of-way between two neighbors whose houses are both fewer than fifteen feet away from our own. But yeah, ventilation and circulation are a huge hassle, because our basement has no windows. In the winter the air down there is bone-dry, and in the spring/summer it gets so damp that we have to be constantly vigilant for mold.
An update on our current grow: ALL FOUR SEEDLINGS ARE MALE! What a bummer. I keep telling my husband that we need to go with clones but he has this fixation on starting seeds. We've been doing this for about twelve years now and we've achieved a certain level of sophistication through the good old "denial and error" process, so honestly, I fail to see the point of this insistence on relying on bag seed. Oh, well, at least the regenerated females are all doing well.